Motif ID: HOX{A6,A7,B6,B7}.p2

Z-value: 4.212


Transcription factors associated with HOX{A6,A7,B6,B7}.p2:

Gene SymbolEntrez IDGene Name
HOXA6 3203 homeobox A6
HOXA7 3204 homeobox A7
HOXB6 3216 homeobox B6
HOXB7 3217 homeobox B7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXA6hg19_v1_chr7_-_27187367_271873920.318.4e-02Click!
HOXB7hg19_v1_chr17_-_46688362_466883820.271.3e-01Click!
HOXA7hg19_v1_chr7_-_27196163_271963280.232.0e-01Click!
HOXB6hg19_v1_chr17_-_46682333_466823560.232.1e-01Click!


Activity profile for motif HOX{A6,A7,B6,B7}.p2.

activity profile for motif HOX{A6,A7,B6,B7}.p2


Sorted Z-values histogram for motif HOX{A6,A7,B6,B7}.p2

Sorted Z-values for motif HOX{A6,A7,B6,B7}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A6,A7,B6,B7}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_7382750 33.879 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr12_-_16760935 27.938 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr5_+_71502700 24.951 MAP1B
microtubule-associated protein 1B
chr9_-_14086901 22.637 NFIB
nuclear factor I/B
chr12_-_87232635 20.389 NM_013244
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr3_+_159557745 20.177 SCHIP1
schwannomin interacting protein 1
chr1_-_217113007 19.395 NM_001243512
NM_001243513
NM_001243510
NM_001243511
ESRRG



estrogen-related receptor gamma



chr1_-_217250230 18.910 NM_001243507
NM_001243509
ESRRG

estrogen-related receptor gamma

chr3_+_127641901 18.183 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr9_-_95186559 18.053 NM_005014
OMD
osteomodulin
chr2_+_170366211 17.810 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr2_-_183387063 17.749 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr18_-_40857245 16.919 NM_020783
SYT4
synaptotagmin IV
chr3_+_35721115 16.334 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr3_+_159557649 16.103 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr12_+_41831484 16.012 NM_013377
PDZRN4
PDZ domain containing ring finger 4
chr7_-_107880492 15.964 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr6_-_123957941 15.941 NM_001251987
NM_006073
TRDN

triadin

chrX_+_102585113 15.915 NM_152278
TCEAL7
transcription elongation factor A (SII)-like 7
chr3_+_158787040 15.629 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr10_-_21186530 15.625 NM_006393
NEBL
nebulette
chr13_-_36050758 15.473 NM_005584
MAB21L1
mab-21-like 1 (C. elegans)
chr10_+_69869249 15.393 NM_032578
MYPN
myopalladin
chrX_-_137821514 15.355 NM_033642
FGF13
fibroblast growth factor 13
chr7_+_107110501 13.739 NM_005295
GPR22
G protein-coupled receptor 22
chr13_-_103054027 13.728 NM_175929
FGF14
fibroblast growth factor 14
chr4_-_176733413 13.618 GPM6A
glycoprotein M6A
chr5_+_59784004 13.581 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr1_+_170632274 13.490 PRRX1
paired related homeobox 1
chr9_-_8733893 13.287 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr18_+_32290195 13.213 NM_001198941
NM_032978
DTNA

dystrobrevin, alpha

chr2_-_224467049 13.059 SCG2
secretogranin II
chr5_+_161494647 12.820 NM_000816
NM_198903
NM_198904
GABRG2


gamma-aminobutyric acid (GABA) A receptor, gamma 2


chr6_+_12716887 12.333 PHACTR1
phosphatase and actin regulator 1
chr4_+_41614911 12.279 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr2_+_210444364 12.068 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr4_+_41614725 12.012 LIMCH1
LIM and calponin homology domains 1
chr14_+_101295409 11.997 MEG3
maternally expressed 3 (non-protein coding)
chr11_+_99426872 11.796 NM_175566
CNTN5
contactin 5
chr6_-_76203256 11.776 NM_015687
FILIP1
filamin A interacting protein 1
chr4_-_176733378 11.648 GPM6A
glycoprotein M6A
chr18_+_32173281 11.590 NM_001128175
NM_001198938
NM_001198939
NM_001198940
DTNA



dystrobrevin, alpha



chr9_+_109686436 11.480 ZNF462
zinc finger protein 462
chr2_-_198540583 11.327 NM_144629
RFTN2
raftlin family member 2
chr18_-_3845295 11.206 NM_001003809
NM_001242765
NM_001242766
DLGAP1


discs, large (Drosophila) homolog-associated protein 1


chr10_+_24755459 11.121 KIAA1217
KIAA1217
chr4_+_113970784 10.993 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr11_-_4718948 10.858 NM_030774
OR51E2
olfactory receptor, family 51, subfamily E, member 2
chr4_+_41614933 10.748 LIMCH1
LIM and calponin homology domains 1
chr17_-_10452939 10.677 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chr6_+_54173202 10.666 NM_014464
TINAG
tubulointerstitial nephritis antigen
chr12_-_99548867 10.652 NM_001204067
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr9_+_12693385 10.483 NM_000550
TYRP1
tyrosinase-related protein 1
chr9_+_130026755 10.400 NM_032293
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr2_-_200325200 10.283 SATB2
SATB homeobox 2
chr17_-_10421858 10.115 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr12_-_16758312 10.094 NM_001243611
LMO3
LIM domain only 3 (rhombotin-like 2)
chr11_+_131240370 10.076 NM_001048209
NTM
neurotrimin
chr4_+_41700736 10.024 LIMCH1
LIM and calponin homology domains 1
chr4_-_176733901 9.907 GPM6A
glycoprotein M6A
chr12_-_91576805 9.855 NM_001920
DCN
decorin
chrX_-_32430370 9.744 NM_004011
NM_004012
DMD

dystrophin

chrX_+_85517970 9.690 NM_001139515
DACH2
dachshund homolog 2 (Drosophila)
chr1_+_160160284 9.682 NM_001231
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr12_-_16758839 9.653 NM_001243612
LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_-_18690187 9.652 NM_000330
RS1
retinoschisin 1
chr2_-_77749335 9.483 NM_001134745
NM_024993
LRRTM4

leucine rich repeat transmembrane neuronal 4

chr7_-_31380507 9.442 NM_022728
NEUROD6
neurogenic differentiation 6
chr2_-_224467095 9.431 SCG2
secretogranin II
chr5_+_126984712 9.398 NM_001048252
CTXN3
cortexin 3
chr5_+_137203559 9.226 MYOT
myotilin
chr14_+_76837689 9.141 NM_004452
ESRRB
estrogen-related receptor beta
chr8_+_92261515 9.054 NM_052832
NM_134266
SLC26A7

solute carrier family 26, member 7

chr3_+_173116243 9.032 NM_014932
NLGN1
neuroligin 1
chr5_-_141993691 8.959 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chr2_+_166428845 8.927 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr5_+_36606667 8.910 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_+_48498497 8.871 NM_000338
NM_001184832
SLC12A1

solute carrier family 12 (sodium/potassium/chloride transporters), member 1

chr1_+_50574601 8.854 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr12_-_71031174 8.830 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr8_-_82395401 8.735 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr2_-_161056762 8.720 ITGB6
integrin, beta 6
chr17_+_22022436 8.702 NM_001190452
MTRNR2L1
MT-RNR2-like 1
chrX_+_28605558 8.659 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr2_+_182850550 8.618 NM_001080545
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr2_-_224467142 8.554 NM_003469
SCG2
secretogranin II
chr12_-_16759430 8.549 LMO3
LIM domain only 3 (rhombotin-like 2)
chr13_-_38172862 8.524 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr5_+_36606456 8.493 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chrX_-_117119282 8.466 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr13_+_36050885 8.452 NM_001204197
NBEA
neurobeachin
chr3_+_115342302 8.443 GAP43
growth associated protein 43
chr7_+_114055234 8.428 FOXP2
forkhead box P2
chr5_+_137203544 8.416 NM_001135940
NM_006790
MYOT

myotilin

chr18_+_32073245 8.395 NM_001198945
NM_001392
NM_032975
NM_032979
DTNA



dystrobrevin, alpha



chr15_+_43885251 8.373 NM_020990
CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chr5_-_160279045 8.322 NM_025153
ATP10B
ATPase, class V, type 10B
chr12_-_16759733 8.272 NM_001243610
LMO3
LIM domain only 3 (rhombotin-like 2)
chr16_-_51185150 8.220 NM_002968
SALL1
sal-like 1 (Drosophila)
chr1_-_190446701 8.212 NM_199051
FAM5C
family with sequence similarity 5, member C
chr9_-_95166827 8.206 NM_014057
NM_033014
OGN

osteoglycin

chr1_-_216896640 8.176 NM_001243515
NM_001243518
NM_001243519
NM_001438
ESRRG



estrogen-related receptor gamma



chr10_+_24755440 8.174 KIAA1217
KIAA1217
chr5_+_139505519 8.145 NM_001007189
IGIP
IgA-inducing protein homolog (Bos taurus)
chr21_-_39870303 8.138 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr12_-_15865847 8.088 EPS8
epidermal growth factor receptor pathway substrate 8
chr3_+_63428752 8.076 NM_144642
SYNPR
synaptoporin
chr18_-_53089722 7.959 NM_001243233
TCF4
transcription factor 4
chr17_+_68071386 7.948 NM_018658
NM_170741
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr12_-_91576579 7.914 DCN
decorin
chr3_+_135741576 7.885 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr10_+_45406629 7.862 NM_001123376
TMEM72
transmembrane protein 72
chrX_+_135278912 7.853 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr3_+_181417387 7.848 SOX2-OT
SOX2 overlapping transcript (non-protein coding)
chr10_-_69455926 7.814 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr12_-_16759420 7.798 LMO3
LIM domain only 3 (rhombotin-like 2)
chr18_-_64271215 7.794 NM_021153
CDH19
cadherin 19, type 2
chr12_-_16759531 7.786 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr22_-_37098620 7.776 NM_006078
CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chr13_-_36429798 7.758 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr3_-_69171536 7.738 NM_198271
LMOD3
leiomodin 3 (fetal)
chr4_-_186877869 7.736 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr9_+_103340335 7.703 NM_001018116
MURC
muscle-related coiled-coil protein
chr3_-_167191808 7.684 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr15_+_71839540 7.659 THSD4
thrombospondin, type I, domain containing 4
chr14_+_62462540 7.585 NM_031914
SYT16
synaptotagmin XVI
chr4_+_113739203 7.529 NM_001127493
ANK2
ankyrin 2, neuronal
chr8_+_80523376 7.526 STMN2
stathmin-like 2
chr10_+_68685791 7.513 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr2_-_161056573 7.494 NM_000888
ITGB6
integrin, beta 6
chr3_+_35722428 7.460 NM_198399
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr12_-_16757944 7.456 LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_+_104831415 7.407 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr18_+_59157774 7.385 NM_031891
CDH20
cadherin 20, type 2
chr9_-_19786886 7.322 NM_001193288
NM_020344
SLC24A2

solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

chr4_-_186733372 7.275 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr5_-_96478502 7.218 NM_153234
LIX1
Lix1 homolog (chicken)
chr18_-_3874252 7.215 NM_001242764
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr1_-_203055088 7.209 MYOG
myogenin (myogenic factor 4)
chr10_+_95517565 7.153 NM_005097
LGI1
leucine-rich, glioma inactivated 1
chr11_+_101983170 7.126 NM_001195045
YAP1
Yes-associated protein 1
chr16_+_6823809 7.124 NM_001142334
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_-_24645084 7.123 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chrX_-_32173585 7.113 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr5_-_124080773 7.030 NM_020747
ZNF608
zinc finger protein 608
chr22_-_36236421 6.982 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chrX_-_13835313 6.966 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr1_+_215178884 6.966 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr4_+_88896801 6.956 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr5_+_166711842 6.954 NM_001122679
ODZ2
odz, odd Oz/ten-m homolog 2 (Drosophila)
chr2_-_233641225 6.924 NM_001172416
NM_001172417
NM_002242
KCNJ13


potassium inwardly-rectifying channel, subfamily J, member 13


chr12_-_117799410 6.922 NM_000620
NM_001204218
NOS1

nitric oxide synthase 1 (neuronal)

chr4_-_21699317 6.908 NM_001035003
KCNIP4
Kv channel interacting protein 4
chr10_-_75335415 6.873 NM_152586
USP54
ubiquitin specific peptidase 54
chr11_+_113775517 6.866 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr4_-_87770267 6.857 NM_197965
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr6_+_121756744 6.851 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr3_+_25470067 6.848 RARB
retinoic acid receptor, beta
chr4_+_71494460 6.827 NM_031889
ENAM
enamelin
chr11_+_27015668 6.783


chr5_+_174151531 6.755 NM_002449
MSX2
msh homeobox 2
chr13_+_96085852 6.718 NM_001160100
NM_182848
CLDN10

claudin 10

chr1_-_178840079 6.679 NM_004673
ANGPTL1
angiopoietin-like 1
chr11_-_8285299 6.667 NM_002315
LMO1
LIM domain only 1 (rhombotin 1)
chr11_+_27015627 6.639 NM_203371
FIBIN
fin bud initiation factor homolog (zebrafish)
chr17_-_10372875 6.617 NM_017533
MYH4
myosin, heavy chain 4, skeletal muscle
chr2_-_105467912 6.610 LOC100506421
uncharacterized LOC100506421
chr4_-_186877413 6.596 SORBS2
sorbin and SH3 domain containing 2
chr10_+_95848811 6.565 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr12_+_119616594 6.560 NM_014365
HSPB8
heat shock 22kDa protein 8
chr3_+_2280512 6.548 NM_001206955
CNTN4
contactin 4
chr4_+_88896838 6.522 SPP1
secreted phosphoprotein 1
chr11_-_111782447 6.518 NM_001885
CRYAB
crystallin, alpha B
chr11_-_115088628 6.502 CADM1
cell adhesion molecule 1
chr10_-_62149487 6.492 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr1_+_81771844 6.485 LPHN2
latrophilin 2
chr1_+_65730423 6.469 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr7_+_114055048 6.325 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr18_+_616671 6.321 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr4_+_88896868 6.312 SPP1
secreted phosphoprotein 1
chr8_+_77593522 6.254 ZFHX4
zinc finger homeobox 4
chr8_+_80523351 6.251 STMN2
stathmin-like 2
chr18_-_31628557 6.236 NM_001198549
NOL4
nucleolar protein 4
chr13_-_70682458 6.235 NM_020866
KLHL1
kelch-like 1 (Drosophila)
chr6_-_46293628 6.235 NM_005822
RCAN2
regulator of calcineurin 2
chrX_-_13835187 6.163 GPM6B
glycoprotein M6B
chr11_-_26743545 6.162 NM_178498
SLC5A12
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr3_+_42190825 6.156 TRAK1
trafficking protein, kinesin binding 1
chr5_-_96478438 6.144 LIX1
Lix1 homolog (chicken)
chr2_+_210444154 6.144 MAP2
microtubule-associated protein 2
chr6_-_24383519 6.099 NM_001195610
DCDC2
doublecortin domain containing 2
chr22_-_36236264 6.083 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr6_-_116381765 6.080 NM_002031
FRK
fyn-related kinase
chr8_+_77593506 6.067 NM_024721
ZFHX4
zinc finger homeobox 4
chr14_+_32798478 6.062 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chrX_-_31526414 6.020 NM_004014
DMD
dystrophin
chr17_-_29624249 5.996 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chr1_+_177140062 5.989 FAM5B
family with sequence similarity 5, member B
chr4_+_88896899 5.989 SPP1
secreted phosphoprotein 1
chr8_+_80523048 5.988 NM_001199214
NM_007029
STMN2

stathmin-like 2


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.00 6.51e-30 GO:0048731 system development
1.64 4.11e-29 GO:0032501 multicellular organismal process
1.84 1.77e-27 GO:0007275 multicellular organismal development
1.88 7.74e-27 GO:0048856 anatomical structure development
1.78 8.54e-27 GO:0032502 developmental process
6.70 4.22e-24 GO:0007156 homophilic cell adhesion
2.35 1.71e-23 GO:0007399 nervous system development
2.91 3.23e-21 GO:0007155 cell adhesion
2.91 3.23e-21 GO:0022610 biological adhesion
4.13 3.84e-19 GO:0016337 cell-cell adhesion
2.09 9.65e-16 GO:0009653 anatomical structure morphogenesis
1.84 1.31e-13 GO:0030154 cell differentiation
1.81 4.67e-13 GO:0048869 cellular developmental process
2.32 1.07e-12 GO:0022008 neurogenesis
2.34 3.09e-12 GO:0048699 generation of neurons
2.32 3.04e-10 GO:0007267 cell-cell signaling
2.39 3.28e-10 GO:0030182 neuron differentiation
2.16 5.85e-10 GO:0048468 cell development
1.80 8.29e-10 GO:0003008 system process
1.74 2.11e-09 GO:0048513 organ development
2.07 2.28e-09 GO:0007154 cell communication
2.54 1.62e-08 GO:0000904 cell morphogenesis involved in differentiation
2.35 1.65e-08 GO:0032989 cellular component morphogenesis
3.58 4.10e-08 GO:0007517 muscle organ development
2.34 7.58e-08 GO:0000902 cell morphogenesis
2.49 8.62e-08 GO:0031175 neuron projection development
2.36 1.02e-07 GO:0048666 neuron development
2.57 1.14e-07 GO:0048812 neuron projection morphogenesis
2.45 2.46e-07 GO:0019226 transmission of nerve impulse
2.45 2.46e-07 GO:0035637 multicellular organismal signaling
1.43 3.21e-07 GO:0023052 signaling
2.56 3.83e-07 GO:0007409 axonogenesis
2.52 5.04e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
2.38 7.15e-07 GO:0032990 cell part morphogenesis
2.37 1.38e-06 GO:0048858 cell projection morphogenesis
2.47 1.45e-06 GO:0007268 synaptic transmission
2.89 1.65e-06 GO:0061061 muscle structure development
2.73 2.75e-06 GO:0001501 skeletal system development
1.89 5.55e-06 GO:0009605 response to external stimulus
5.31 6.54e-06 GO:0007519 skeletal muscle tissue development
3.55 8.12e-06 GO:0043062 extracellular structure organization
2.13 8.62e-06 GO:0030030 cell projection organization
2.16 1.08e-05 GO:0009887 organ morphogenesis
2.26 1.46e-05 GO:0007417 central nervous system development
1.93 1.53e-05 GO:0009888 tissue development
5.62 1.93e-05 GO:0050808 synapse organization
4.99 1.97e-05 GO:0060538 skeletal muscle organ development
3.54 5.89e-05 GO:0060537 muscle tissue development
2.50 8.49e-05 GO:0007411 axon guidance
3.51 1.34e-04 GO:0048705 skeletal system morphogenesis
3.45 1.84e-04 GO:0001503 ossification
3.56 1.88e-04 GO:0014706 striated muscle tissue development
2.49 2.07e-04 GO:0060284 regulation of cell development
3.12 2.60e-04 GO:0006936 muscle contraction
1.64 2.93e-04 GO:0050877 neurological system process
4.17 4.02e-04 GO:0048706 embryonic skeletal system development
2.98 4.37e-04 GO:0003012 muscle system process
7.62 4.64e-04 GO:0016339 calcium-dependent cell-cell adhesion
2.99 6.45e-04 GO:0030900 forebrain development
3.13 1.21e-03 GO:0001655 urogenital system development
9.14 1.41e-03 GO:0007026 negative regulation of microtubule depolymerization
2.31 1.42e-03 GO:0007389 pattern specification process
2.04 1.89e-03 GO:0006935 chemotaxis
2.04 1.89e-03 GO:0042330 taxis
3.45 2.20e-03 GO:0072001 renal system development
2.59 2.39e-03 GO:0048568 embryonic organ development
8.60 2.53e-03 GO:0031114 regulation of microtubule depolymerization
1.86 3.76e-03 GO:0010628 positive regulation of gene expression
2.94 3.86e-03 GO:0048562 embryonic organ morphogenesis
2.40 4.25e-03 GO:0051960 regulation of nervous system development
4.41 4.35e-03 GO:0048704 embryonic skeletal system morphogenesis
1.81 8.77e-03 GO:0009790 embryo development
2.15 9.06e-03 GO:0043009 chordate embryonic development
1.69 9.75e-03 GO:0050793 regulation of developmental process
5.71 1.02e-02 GO:0007416 synapse assembly
3.02 1.09e-02 GO:0006814 sodium ion transport
3.02 1.09e-02 GO:0034329 cell junction assembly
1.99 1.11e-02 GO:0072358 cardiovascular system development
1.99 1.11e-02 GO:0072359 circulatory system development
2.13 1.21e-02 GO:0009792 embryo development ending in birth or egg hatching
2.00 1.33e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.69 1.53e-02 GO:0006811 ion transport
1.70 1.61e-02 GO:0040011 locomotion
1.31 1.64e-02 GO:0007165 signal transduction
2.19 1.73e-02 GO:0051093 negative regulation of developmental process
2.38 1.90e-02 GO:0050767 regulation of neurogenesis
2.83 1.95e-02 GO:0045165 cell fate commitment
2.09 2.32e-02 GO:0048598 embryonic morphogenesis
1.95 2.45e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.87 2.79e-02 GO:0007186 G-protein coupled receptor protein signaling pathway
2.26 3.00e-02 GO:0035295 tube development
3.13 3.04e-02 GO:0048736 appendage development
3.13 3.04e-02 GO:0060173 limb development
2.50 3.15e-02 GO:0045664 regulation of neuron differentiation
2.08 3.38e-02 GO:0007420 brain development
1.62 3.51e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
6.36 3.80e-02 GO:0031111 negative regulation of microtubule polymerization or depolymerization
1.18 4.38e-02 GO:0050794 regulation of cellular process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.65 3.72e-23 GO:0005886 plasma membrane
1.64 1.28e-22 GO:0071944 cell periphery
1.89 1.40e-18 GO:0044459 plasma membrane part
3.20 2.83e-15 GO:0045202 synapse
5.36 7.91e-14 GO:0030016 myofibril
5.20 8.00e-14 GO:0043292 contractile fiber
2.55 4.49e-12 GO:0030054 cell junction
5.01 1.25e-11 GO:0044449 contractile fiber part
2.04 2.45e-10 GO:0044421 extracellular region part
4.08 1.09e-09 GO:0045211 postsynaptic membrane
3.05 1.42e-09 GO:0044456 synapse part
4.85 3.32e-09 GO:0030017 sarcomere
1.63 1.62e-08 GO:0005576 extracellular region
1.29 3.71e-08 GO:0044425 membrane part
2.58 5.05e-08 GO:0043005 neuron projection
1.24 6.19e-08 GO:0016020 membrane
2.75 1.43e-07 GO:0005578 proteinaceous extracellular matrix
2.58 1.54e-07 GO:0031012 extracellular matrix
1.74 1.82e-06 GO:0031226 intrinsic to plasma membrane
1.71 8.99e-06 GO:0005887 integral to plasma membrane
1.86 1.17e-05 GO:0042995 cell projection
1.27 1.38e-05 GO:0031224 intrinsic to membrane
1.89 1.75e-05 GO:0005615 extracellular space
4.17 6.45e-05 GO:0014069 postsynaptic density
1.25 3.07e-04 GO:0016021 integral to membrane
2.55 3.45e-04 GO:0016323 basolateral plasma membrane
2.64 3.81e-04 GO:0034702 ion channel complex
3.07 3.80e-03 GO:0044420 extracellular matrix part
2.53 4.18e-03 GO:0030425 dendrite
2.84 4.66e-03 GO:0034703 cation channel complex
7.11 8.92e-03 GO:0005859 muscle myosin complex
7.11 8.92e-03 GO:0032982 myosin filament
2.11 1.45e-02 GO:0015629 actin cytoskeleton
10.15 1.68e-02 GO:0031143 pseudopodium
6.40 1.97e-02 GO:0016460 myosin II complex
7.31 2.86e-02 GO:0034706 sodium channel complex
1.41 4.20e-02 GO:0005856 cytoskeleton
4.06 4.24e-02 GO:0030666 endocytic vesicle membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.65 4.29e-15 GO:0005509 calcium ion binding
2.85 1.43e-08 GO:0003779 actin binding
2.34 4.57e-08 GO:0008092 cytoskeletal protein binding
2.34 7.13e-06 GO:0015267 channel activity
2.33 7.75e-06 GO:0022803 passive transmembrane transporter activity
1.79 1.92e-05 GO:0001071 nucleic acid binding transcription factor activity
1.79 1.92e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
2.27 4.84e-05 GO:0022838 substrate-specific channel activity
5.53 1.40e-04 GO:0008307 structural constituent of muscle
2.21 1.96e-04 GO:0005216 ion channel activity
2.37 2.51e-04 GO:0022836 gated channel activity
1.88 3.02e-04 GO:0043565 sequence-specific DNA binding
1.73 3.04e-04 GO:0022857 transmembrane transporter activity
1.81 4.94e-04 GO:0015075 ion transmembrane transporter activity
1.58 2.07e-03 GO:0005215 transporter activity
2.76 2.88e-03 GO:0001871 pattern binding
2.76 2.88e-03 GO:0030247 polysaccharide binding
1.66 4.78e-03 GO:0022891 substrate-specific transmembrane transporter activity
2.93 7.02e-03 GO:0015276 ligand-gated ion channel activity
2.93 7.02e-03 GO:0022834 ligand-gated channel activity
2.74 7.97e-03 GO:0008509 anion transmembrane transporter activity
2.96 1.54e-02 GO:0008201 heparin binding
2.61 2.49e-02 GO:0005539 glycosaminoglycan binding
2.15 2.54e-02 GO:0005261 cation channel activity
7.83 2.61e-02 GO:0005248 voltage-gated sodium channel activity